Updated: Jan 17
We have been searching for clues to the obesity epidemic for over 40 years. There is a cascade of physiologic events driving this obesity epidemic but we now know that we are able to intervene in multiple areas of this cascade toward obesity.
Calorie-dense starches and sugary foods deliver informational signals to certain gut bacteria. These bacteria are known to help us during times of survival. They also divert calories to the liver to assist with food storage. The calories are stored as fat, instead of creating energy for muscle. We gain weight, as though we were in a survival situation, as our body thinks it needs to conserve every calorie. Weight gain can occur when consuming calorie-dense foods and those high in sugar, even if you are restricting yourself in other areas.
These survival bacteria are also known to cause inflammation if they are overly prevalent. Eighty percent of our lymph nodes are located near the small intestine. When these lymph nodes are under stress they send out inflammatory cytokines, which circulate in the body, causing a now worried immune system to attack our internal organs. This type of inflammation causes certain transcription factors, which are intracellular messengers, to elevate. This leads to oxidization of multiple targets, a process called oxidative phosphorylation. One of the most common targets in this attack are the bodies insulin receptors.
Insulin receptors are needed to provide a way for insulin to help food calories enter a cell. When insulin receptors are healthy, we easily receive the insulin which fits like a key in a keyhole and opens the door to allow food into the cell. If the insulin receptors are oxidized, they are rendered inactive and food cannot get in the cells. This leaves us feeling weak and our blood sugars rise as well, (Journal of Antioxidants and Redox Signaling Vol. 7 Issue 7-8 July 2005 ).
At every step of the cascade towards obesity, supplementing REDOX molecules can help weight regulation. Friendly bacteria thrive in the presence of REDOX molecules. Unhealthy bacteria do not tolerate the healthy REDOX balance, which make them unable to replicate at the same rates as friendly bacteria. By choosing micro biome friendly foods like fruits, vegetables, lean meats, legumes, and eggs you will also increase the health of your micro biome.
REDOX molecules, in a balanced formulation, provide the needed resources for reducing inflammation by activating the effectiveness of our native antioxidants like glutathione. These antioxidants will inhibit the degradation of insulin receptors and lead to a more youthful metabolic picture, including weight balance.